Tip: More Relics on Normal

You've been running dungeons on normal for easy xp, but you feel sad whenever the relic box gives you one common relic. You might as well switch difficulty to insane before opening that relic box. Now when the relic guardian appears he'll have better drops! (This only works if a Guardian appears.) Don't forget to switch back to normal afterwards. -Peklat

Tip within a tip: Just after opening the relic chest, before the Guardian can spawn his minions, very quickly switch back to normal using the console and his summoned assistants will be normal instead of insane. You'll also be less likely to forget to restore your difficulty afterward.